PDB Information

PDB3IPX
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors.
Jessop, T.C., Tarver, J.E., Carlsen, M., Xu, A., Healy, J.P., Heim-Riether, A., Fu, Q., Taylor, J.A., Augeri, D.J., Shen, M., Stouch, T.R., Swanson, R.V., Tari, L.W., Hunter, M., Hoffman, I., Keyes, P.E., Yu, X.C., Miranda, M., Liu, Q., Swaffield, J.C., David Kimball, S., Nouraldeen, A., Wilson, A.G., Foushee, A.M., Jhaver, K., Finch, R., Anderson, S., Oravecz, T., Carson, K.G.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2009-08-18
Resolution2.000
CATH Insert Date22 Aug, 2010

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 23 Aug, 2010 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3ipxA00 19 Sep, 2010 3.40.50.300 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P27707 DCK_HUMAN Homo sapiens Deoxycytidine kinase