PDB 3iop

PDB Information

PDB3IOP
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1).
Nittoli, T., Dushin, R.G., Ingalls, C., Cheung, K., Floyd, M.B., Fraser, H., Olland, A., Hu, Y., Grosu, G., Han, X., Arndt, K., Guo, B., Wissner, A.
Eur.J.Med.Chem.
HeaderTransferase
Released2009-08-14
Resolution2.200
CATH Insert Date18 Feb, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 18 Feb, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3iopA01 02 Apr, 2010 3.30.200.20 Assigned
3iopA02 02 Apr, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O15530 PDPK1_HUMAN Homo sapiens 3-phosphoinositide-dependent protein kinase 1