PDB Information

PDB3II5
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHomo sapiens
Primary Citation
Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors.
Berger, D.M., Torres, N., Dutia, M., Powell, D., Ciszewski, G., Gopalsamy, A., Levin, J.I., Kim, K.H., Xu, W., Wilhelm, J., Hu, Y., Collins, K., Feldberg, L., Kim, S., Frommer, E., Wojciechowicz, D., Mallon, R.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-07-31
Resolution2.790
CATH Insert Date15 Nov, 2009

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2009 Chopped
B 15 Nov, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3ii5A01 01 Apr, 2010 3.30.200.20 Assigned
3ii5A02 01 Apr, 2010 1.10.510.10 Assigned
3ii5B01 30 Mar, 2010 3.30.200.20 Assigned
3ii5B02 30 Mar, 2010 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
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