PDB Information

PDB3IG6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of orally bioavailable, non-amidine inhibitors of Urokinase Plasminogen Activator (uPA)
West, C.W., Adler, M., Arnaiz, D., Chen, D., Chu, K., Gualtieri, G., Ho, E., Huwe, C., Light, D., Phillips, G., Pulk, R., Sukovich, D., Whitlow, M., Yuan, S., Bryant, J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-07-27
Resolution1.830
CATH Insert Date18 Oct, 2009

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 18 Oct, 2009 Rejected
B 18 Oct, 2009 Chopped
C 18 Oct, 2009 Rejected
D 18 Oct, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3ig6B01 30 Mar, 2010 2.40.10.10 Assigned
3ig6B02 30 Mar, 2010 2.40.10.10 Assigned
3ig6D01 30 Mar, 2010 2.40.10.10 Assigned
3ig6D02 30 Mar, 2010 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00749 UROK_HUMAN Homo sapiens Urokinase-type plasminogen activator
P00749 UROK_HUMAN Homo sapiens Urokinase-type plasminogen activator
P00749 UROK_HUMAN Homo sapiens Urokinase-type plasminogen activator
P00749 UROK_HUMAN Homo sapiens Urokinase-type plasminogen activator