PDB 3hqz

PDB Information

PDB3HQZ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceRattus norvegicus
Primary Citation
Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia
Verhoest, P.R., Chapin, D.S., Corman, M., Fonseca, K., Harms, J.F., Hou, X., Marr, E.S., Menniti, F.S., Nelson, F., O'Connor, R., Pandit, J., Proulx-Lafrance, C., Schmidt, A.W., Schmidt, C.J., Suiciak, J.A., Liras, S.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2009-06-08
Resolution1.700
CATH Insert Date16 Aug, 2009

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3hqzA00 15 Aug, 2010 1.10.1300.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9QYJ6 PDE10_RAT Rattus norvegicus cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
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