PDB 3hqw

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Overview

PDB Information

PDB	3HQW
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Rattus norvegicus
Primary Citation	Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia Verhoest, P.R., Chapin, D.S., Corman, M., Fonseca, K., Harms, J.F., Hou, X., Marr, E.S., Menniti, F.S., Nelson, F., O'Connor, R., Pandit, J., Proulx-Lafrance, C., Schmidt, A.W., Schmidt, C.J., Suiciak, J.A., Liras, S. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2009-06-08
Resolution	1.700
CATH Insert Date	16 Aug, 2009

PDB Images (3)

Image of CATH 3hqw

3hqw

PDB 3hqw

Image of CATH 3hqwA

3hqwA

PDB Chain 3hqwA

Image of CATH 3hqwA00

3hqwA00

CATH Domain 3hqwA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	16 Aug, 2009	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3hqwA00	15 Aug, 2010	1.10.1300.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q9QYJ6	PDE10_RAT	Rattus norvegicus	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A