PDB Information

PDB3HPT
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors.
Shi, Y., Zhang, J., Shi, M., O'Connor, S.P., Bisaha, S.N., Li, C., Sitkoff, D., Pudzianowski, A.T., Chong, S., Klei, H.E., Kish, K., Yanchunas, J., Liu, E.C., Hartl, K.S., Seiler, S.M., Steinbacher, T.E., Schumacher, W.A., Atwal, K.S., Stein, P.D.
Bioorg.Med.Chem.Lett.
HeaderHydrolase, Blood Clotting
Released2009-06-04
Resolution2.190
CATH Insert Date26 Nov, 2009

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 26 Nov, 2009 Chopped
B 26 Nov, 2009 Chopped
C 26 Nov, 2009 Chopped
D 26 Nov, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3hptA01 20 Feb, 2010 2.10.25.10 Assigned
3hptA02 20 Feb, 2010 2.10.25.10 Assigned
3hptB01 20 Feb, 2010 2.40.10.10 Assigned
3hptB02 20 Feb, 2010 2.40.10.10 Assigned
3hptC01 20 Feb, 2010 2.10.25.10 Assigned
3hptC02 20 Feb, 2010 2.10.25.10 Assigned
3hptD01 20 Feb, 2010 2.40.10.10 Assigned
3hptD02 20 Feb, 2010 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X