PDB 3hgz
PDB Information
| PDB | 3HGZ |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme.
J.Mol.Biol.
|
| Header | Hydrolase |
| Released | 2009-05-14 |
| Resolution | 2.910 |
| CATH Insert Date | 10 Dec, 2009 |
PDB Images (13)
3hgz
PDB 3hgz
3hgzA
PDB Chain 3hgzA
3hgzB
PDB Chain 3hgzB
3hgzD
PDB Chain 3hgzD
3hgzE
PDB Chain 3hgzE
3hgzA01
CATH Domain 3hgzA01
3hgzA02
CATH Domain 3hgzA02
3hgzA03
CATH Domain 3hgzA03
3hgzA04
CATH Domain 3hgzA04
3hgzB01
CATH Domain 3hgzB01
3hgzB02
CATH Domain 3hgzB02
3hgzB03
CATH Domain 3hgzB03
3hgzB04
CATH Domain 3hgzB04
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 10 Dec, 2009 | Chopped |
| B | 10 Dec, 2009 | Chopped |
| D | 10 Dec, 2009 | Rejected |
| E | 10 Dec, 2009 | Rejected |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3hgzA01 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 3hgzA02 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 3hgzA03 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 3hgzA04 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 3hgzB01 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 3hgzB02 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 3hgzB03 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
| 3hgzB04 | 30 Aug, 2013 | 3.30.830.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P14735 | IDE_HUMAN | Homo sapiens | Insulin-degrading enzyme |
| P10997 | IAPP_HUMAN | Homo sapiens | Islet amyloid polypeptide |
| P10997 | IAPP_HUMAN | Homo sapiens | Islet amyloid polypeptide |
| P14735 | IDE_HUMAN | Homo sapiens | Insulin-degrading enzyme |
