PDB 3h4v

PDB Information

PDB3H4V
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceLeishmania major
Primary Citation
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development
Cavazzuti, A., Paglietti, G., Hunter, W.N., Gamarro, F., Piras, S., Loriga, M., Allecca, S., Corona, P., McLuskey, K., Tulloch, L., Gibellini, F., Ferrari, S., Costi, M.P.
Proc.Natl.Acad.Sci.USA
HeaderOxidoreductase
Released2009-04-21
Resolution2.400
CATH Insert Date16 Aug, 2009

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
C 16 Aug, 2009 Chopped
D 16 Aug, 2009 Chopped
E 16 Aug, 2009 Chopped
F 16 Aug, 2009 Chopped
G 16 Aug, 2009 Chopped
H 16 Aug, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3h4vA00 26 Jan, 2010 3.40.50.720 Assigned
3h4vB00 27 Jan, 2010 3.40.50.720 Assigned
3h4vC00 27 Jan, 2010 3.40.50.720 Assigned
3h4vD00 26 Jan, 2010 3.40.50.720 Assigned
3h4vE00 27 Jan, 2010 3.40.50.720 Assigned
3h4vF00 26 Jan, 2010 3.40.50.720 Assigned
3h4vG00 27 Jan, 2010 3.40.50.720 Assigned
3h4vH00 26 Jan, 2010 3.40.50.720 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q01782 PTR1_LEIMA Leishmania major Pteridine reductase 1
Q01782 PTR1_LEIMA Leishmania major Pteridine reductase 1
Q01782 PTR1_LEIMA Leishmania major Pteridine reductase 1
Q01782 PTR1_LEIMA Leishmania major Pteridine reductase 1
Q01782 PTR1_LEIMA Leishmania major Pteridine reductase 1
Q01782 PTR1_LEIMA Leishmania major Pteridine reductase 1
Q01782 PTR1_LEIMA Leishmania major Pteridine reductase 1
Q01782 PTR1_LEIMA Leishmania major Pteridine reductase 1