PDB 3h10

PDB Information

PDB3H10
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.
Aliagas-Martin, I., Burdick, D., Corson, L., Dotson, J., Drummond, J., Fields, C., Huang, O.W., Hunsaker, T., Kleinheinz, T., Krueger, E., Liang, J., Moffat, J., Phillips, G., Pulk, R., Rawson, T.E., Ultsch, M., Walker, L., Wiesmann, C., Zhang, B., Zhu, B.Y., Cochran, A.G.
J.Med.Chem.
HeaderTransferase
Released2009-04-10
Resolution2.200
CATH Insert Date16 Aug, 2009

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
D 16 Aug, 2009 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
3h10A01 23 Jan, 2010 3.30.200.20 Assigned
3h10A02 23 Jan, 2010 1.10.510.10 Assigned
3h10B01 23 Jan, 2010 3.30.200.20 Assigned
3h10B02 23 Jan, 2010 1.10.510.10 Assigned
3h10D01 23 Jan, 2010 3.30.200.20 Assigned
3h10D02 23 Jan, 2010 1.10.510.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A