PDB 3gn1

PDB Information

PDB3GN1
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTrypanosoma brucei brucei
Primary Citation
One scaffold, three binding modes: novel and selective pteridine reductase 1 inhibitors derived from fragment hits discovered by virtual screening.
Mpamhanga, C.P., Spinks, D., Tulloch, L.B., Shanks, E.J., Robinson, D.A., Collie, I.T., Fairlamb, A.H., Wyatt, P.G., Frearson, J.A., Hunter, W.N., Gilbert, I.H., Brenk, R.
J.Med.Chem.
HeaderOxidoreductase
Released2009-03-16
Resolution2.000
CATH Insert Date31 Dec, 2009

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 31 Dec, 2009 Chopped
B 31 Dec, 2009 Chopped
C 31 Dec, 2009 Chopped
D 31 Dec, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3gn1A00 09 Jan, 2010 3.40.50.720 Assigned
3gn1B00 09 Jan, 2010 3.40.50.720 Assigned
3gn1C00 09 Jan, 2010 3.40.50.720 Assigned
3gn1D00 08 Jan, 2010 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase