PDB 3gmd

PDB Information

PDB3GMD
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Structure-based design of 7-azaindole-pyrrolidine amides as inhibitors of 11 beta-hydroxysteroid dehydrogenase type I.
Valeur, E., Christmann-Franck, S., Lepifre, F., Carniato, D., Cravo, D., Charon, C., Bozec, S., Musil, D., Hillertz, P., Doare, L., Schmidlin, F., Lecomte, M., Schultz, M., Roche, D.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2009-03-13
Resolution2.280
CATH Insert Date23 Jan, 2011

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
B 24 Jan, 2011 Chopped
C 24 Jan, 2011 Chopped
D 24 Jan, 2011 Chopped
E 24 Jan, 2011 Chopped
F 24 Jan, 2011 Chopped
G 24 Jan, 2011 Chopped
H 24 Jan, 2011 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3gmdA00 16 Feb, 2011 3.40.50.720 Assigned
3gmdB00 17 Feb, 2011 3.40.50.720 Assigned
3gmdC00 17 Feb, 2011 3.40.50.720 Assigned
3gmdD00 17 Feb, 2011 3.40.50.720 Assigned
3gmdE00 17 Feb, 2011 3.40.50.720 Assigned
3gmdF00 17 Feb, 2011 3.40.50.720 Assigned
3gmdG00 16 Feb, 2011 3.40.50.720 Assigned
3gmdH00 17 Feb, 2011 3.40.50.720 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1
P50172 DHI1_MOUSE Mus musculus Corticosteroid 11-beta-dehydrogenase isozyme 1