PDB 3gi2

PDB Information

PDB3GI2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and X-ray crystal structure of classical and nonclassical 2-amino-4-oxo-5-substituted-6-ethylthieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agents.
Gangjee, A., Li, W., Kisliuk, R.L., Cody, V., Pace, J., Piraino, J., Makin, J.
J.Med.Chem.
HeaderOxidoreductase
Released2009-03-05
Resolution1.530
CATH Insert Date01 Oct, 2009

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 01 Oct, 2009 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3gi2A00 26 Dec, 2009 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase