PDB Information

PDB3FRG
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Quinolines as a novel structural class of potent and selective PDE4 inhibitors: optimisation for oral administration.
Lunniss, C.J., Cooper, A.W., Eldred, C.D., Kranz, M., Lindvall, M., Lucas, F.S., Neu, M., Preston, A.G., Ranshaw, L.E., Redgrave, A.J., Ed Robinson, J., Shipley, T.J., Solanke, Y.E., Somers, D.O., Wiseman, J.O.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2009-01-08
Resolution1.700
CATH Insert Date14 Jan, 2010

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Jan, 2010 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
3frgA00 22 Mar, 2011 1.10.1300.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q07343 PDE4B_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4B
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