PDB Information

PDB3ETA
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase.
Patnaik, S., Stevens, K.L., Gerding, R., Deanda, F., Shotwell, J.B., Tang, J., Hamajima, T., Nakamura, H., Leesnitzer, M.A., Hassell, A.M., Shewchuck, L.M., Kumar, R., Lei, H., Chamberlain, S.D.
Bioorg.Med.Chem.Lett.
HeaderSignaling Protein, Transferase
Released2008-10-07
Resolution2.600
CATH Insert Date16 Aug, 2009

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3etaA01 30 Sep, 2009 3.30.200.20 Assigned
3etaA02 30 Sep, 2009 1.10.510.10 Assigned
3etaB01 30 Sep, 2009 3.30.200.20 Assigned
3etaB02 30 Sep, 2009 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P06213 INSR_HUMAN Homo sapiens Insulin receptor
P06213 INSR_HUMAN Homo sapiens Insulin receptor
CATH-Gene3D is a Global Biodata Core Resource Learn more...