PDB Information

PDB3EOC
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Imidazo[5,1-f][1,2,4]triazin-2-amines as novel inhibitors of polo-like kinase 1.
Cheung, M., Kuntz, K.W., Pobanz, M., Salovich, J.M., Wilson, B.J., Andrews, C.W., Shewchuk, L.M., Epperly, A.H., Hassler, D.F., Leesnitzer, M.A., Smith, J.L., Smith, G.K., Lansing, T.J., Mook, R.A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Cell Cycle
Released2008-09-26
Resolution3.200
CATH Insert Date06 Nov, 2008

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 06 Nov, 2008 Chopped
B 06 Nov, 2008 Chopped
C 06 Nov, 2008 Chopped
D 06 Nov, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3eocA01 08 Nov, 2008 3.30.200.20 Assigned
3eocA02 08 Nov, 2008 1.10.510.10 Assigned
3eocB01 08 Nov, 2008 1.10.472.10 Assigned
3eocB02 08 Nov, 2008 1.10.472.10 Assigned
3eocC01 08 Nov, 2008 3.30.200.20 Assigned
3eocC02 08 Nov, 2008 1.10.510.10 Assigned
3eocD01 08 Nov, 2008 1.10.472.10 Assigned
3eocD02 08 Nov, 2008 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2