PDB 3ekn

PDB Information

PDB3EKN
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity.
Chamberlain, S.D., Redman, A.M., Wilson, J.W., Deanda, F., Shotwell, J.B., Gerding, R., Lei, H., Yang, B., Stevens, K.L., Hassell, A.M., Shewchuk, L.M., Leesnitzer, M.A., Smith, J.L., Sabbatini, P., Atkins, C., Groy, A., Rowand, J.L., Kumar, R., Mook, R.A., Moorthy, G., Patnaik, S.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-09-19
Resolution2.200
CATH Insert Date01 Jan, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 01 Jan, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3eknA01 01 Apr, 2009 3.30.200.20 Assigned
3eknA02 01 Apr, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P06213 INSR_HUMAN Homo sapiens Insulin receptor