PDB 3e8n

PDB Information

PDB3E8N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer.
Iverson, C., Larson, G., Lai, C., Yeh, L.T., Dadson, C., Weingarten, P., Appleby, T., Vo, T., Maderna, A., Vernier, J.M., Hamatake, R., Miner, J.N., Quart, B.
Cancer Res.
HeaderTransferase
Released2008-08-20
Resolution2.500
CATH Insert Date03 Sep, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Sep, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3e8nA01 23 Jan, 2013 3.30.200.20 Assigned
3e8nA02 23 Jan, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q02750 MP2K1_HUMAN Homo sapiens Dual specificity mitogen-activated protein kinase kinase 1