PDB Information

PDB3DU8
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery.
Menichincheri, M., Bargiotti, A., Berthelsen, J., Bertrand, J.A., Bossi, R., Ciavolella, A., Cirla, A., Cristiani, C., Croci, V., D'Alessio, R., Fasolini, M., Fiorentini, F., Forte, B., Isacchi, A., Martina, K., Molinari, A., Montagnoli, A., Orsini, P., Orzi, F., Pesenti, E., Pezzetta, D., Pillan, A., Poggesi, I., Roletto, F., Scolaro, A., Tato, M., Tibolla, M., Valsasina, B., Varasi, M., Volpi, D., Santocanale, C., Vanotti, E.
J.Med.Chem.
HeaderTransferase
Released2008-07-17
Resolution2.200
CATH Insert Date05 Mar, 2009

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2009 Chopped
B 05 Mar, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3du8A01 07 Mar, 2009 3.30.200.20 Assigned
3du8A02 07 Mar, 2009 1.10.510.10 Assigned
3du8B01 07 Mar, 2009 3.30.200.20 Assigned
3du8B02 07 Mar, 2009 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta
P49841 GSK3B_HUMAN Homo sapiens Glycogen synthase kinase-3 beta