PDB Information

PDB3DKG
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Buchanan, S.G., Hendle, J., Lee, P.S., Smith, C.R., Bounaud, P.Y., Jessen, K.A., Tang, C.M., Huser, N.H., Felce, J.D., Froning, K.J., Peterman, M.C., Aubol, B.E., Gessert, S.F., Sauder, J.M., Schwinn, K.D., Russell, M., Rooney, I.A., Adams, J., Leon, B.C., Do, T.H., Blaney, J.M., Sprengeler, P.A., Thompson, D.A., Smyth, L., Pelletier, L.A., Atwell, S., Holme, K., Wasserman, S.R., Emtage, S., Burley, S.K., Reich, S.H.
Mol.Cancer Ther.
HeaderOncoprotein
Released2008-06-24
Resolution1.910
CATH Insert Date16 Aug, 2009

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3dkgA01 16 Sep, 2009 3.30.200.20 Assigned
3dkgA02 16 Sep, 2009 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor