PDB Information

PDB3DGA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria.
Dasgupta, T., Chitnumsub, P., Kamchonwongpaisan, S., Maneeruttanarungroj, C., Nichols, S.E., Lyons, T.M., Tirado-Rives, J., Jorgensen, W.L., Yuthavong, Y., Anderson, K.S.
Acs Chem.Biol.
HeaderOxidoreductase, Transferase
Released2008-06-13
Resolution2.700
CATH Insert Date29 Jan, 2009

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jan, 2009 Chopped
B 29 Jan, 2009 Chopped
C 29 Jan, 2009 Chopped
D 29 Jan, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3dgaA00 19 Feb, 2009 3.40.430.10 Assigned
3dgaB00 19 Feb, 2009 3.40.430.10 Assigned
3dgaC00 19 Feb, 2009 3.30.572.10 Assigned
3dgaD00 19 Feb, 2009 3.30.572.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P13922 DRTS_PLAFK Plasmodium falciparum K1 Bifunctional dihydrofolate reductase-thymidylate synthase
P13922 DRTS_PLAFK Plasmodium falciparum K1 Bifunctional dihydrofolate reductase-thymidylate synthase
P13922 DRTS_PLAFK Plasmodium falciparum K1 Bifunctional dihydrofolate reductase-thymidylate synthase
P13922 DRTS_PLAFK Plasmodium falciparum K1 Bifunctional dihydrofolate reductase-thymidylate synthase
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