PDB Information

PDB3DG8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria.
Dasgupta, T., Chitnumsub, P., Kamchonwongpaisan, S., Maneeruttanarungroj, C., Nichols, S.E., Lyons, T.M., Tirado-Rives, J., Jorgensen, W.L., Yuthavong, Y., Anderson, K.S.
Acs Chem.Biol.
HeaderOxidoreductase, Transferase
Released2008-06-13
Resolution2.580
CATH Insert Date29 Jan, 2009

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jan, 2009 Chopped
B 29 Jan, 2009 Chopped
C 29 Jan, 2009 Chopped
D 29 Jan, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3dg8A00 18 Feb, 2009 3.40.430.10 Assigned
3dg8B00 19 Feb, 2009 3.40.430.10 Assigned
3dg8C00 18 Feb, 2009 3.30.572.10 Assigned
3dg8D00 19 Feb, 2009 3.30.572.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P13922 DRTS_PLAFK Plasmodium falciparum K1 Bifunctional dihydrofolate reductase-thymidylate synthase
P13922 DRTS_PLAFK Plasmodium falciparum K1 Bifunctional dihydrofolate reductase-thymidylate synthase
P13922 DRTS_PLAFK Plasmodium falciparum K1 Bifunctional dihydrofolate reductase-thymidylate synthase
P13922 DRTS_PLAFK Plasmodium falciparum K1 Bifunctional dihydrofolate reductase-thymidylate synthase
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