PDB 3cwe

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Overview

PDB Information

PDB	3CWE
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor Han, Y., Belley, M., Bayly, C.I., Colucci, J., Dufresne, C., Giroux, A., Lau, C.K., Leblanc, Y., McKay, D., Therien, M., Wilson, M.C., Skorey, K., Chan, C.C., Scapin, G., Kennedy, B.P. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2008-04-21
Resolution	1.600
CATH Insert Date	23 Jul, 2008

PDB Images (3)

Image of CATH 3cwe

3cwe

PDB 3cwe

Image of CATH 3cweA

3cweA

PDB Chain 3cweA

Image of CATH 3cweA00

3cweA00

CATH Domain 3cweA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	24 Jul, 2008	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
3cweA00	25 Jul, 2008	3.90.190.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P18031	PTN1_HUMAN	Homo sapiens	Tyrosine-protein phosphatase non-receptor type 1