Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.
Harris, P.A., Boloor, A., Cheung, M., Kumar, R., Crosby, R.M., Davis-Ward, R.G., Epperly, A.H., Hinkle, K.W., Hunter, R.N., Johnson, J.H., Knick, V.B., Laudeman, C.P., Luttrell, D.K., Mook, R.A., Nolte, R.T., Rudolph, S.K., Szewczyk, J.R., Truesdale, A.T., Veal, J.M., Wang, L., Stafford, J.A.
J.Med.Chem.