PDB 3cic

PDB Information

PDB3CIC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors
Cumming, J.N., Le, T.X., Babu, S., Carroll, C., Chen, X., Favreau, L., Gaspari, P., Guo, T., Hobbs, D.W., Huang, Y., Iserloh, U., Kennedy, M.E., Kuvelkar, R., Li, G., Lowrie, J., McHugh, N.A., Ozgur, L., Pan, J., Parker, E.M., Saionz, K., Stamford, A.W., Strickland, C., Tadesse, D., Voigt, J., Wang, L., Wu, Y., Zhang, L., Zhang, Q.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2008-03-11
Resolution1.750
CATH Insert Date23 Jul, 2008

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3cicA01 26 Jul, 2008 2.40.70.10 Assigned
3cicA02 26 Jul, 2008 2.40.70.10 Assigned
3cicB01 26 Jul, 2008 2.40.70.10 Assigned
3cicB02 26 Jul, 2008 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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