PDB Information

PDB3C8N
MethodX-RAY DIFFRACTION
Host OrganismMycobacterium smegmatis
Gene SourceMycobacterium tuberculosis
Primary Citation
Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding.
Bashiri, G., Squire, C.J., Moreland, N.J., Baker, E.N.
J.Biol.Chem.
HeaderOxidoreductase
Released2008-02-12
Resolution1.900
CATH Insert Date27 Apr, 2008

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 27 Apr, 2008 Chopped
B 27 Apr, 2008 Chopped
C 27 Apr, 2008 Chopped
D 27 Apr, 2008 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3c8nA00 14 Mar, 2013 3.20.20.30 Assigned
3c8nB00 20 Oct, 2008 3.20.20.30 Assigned
3c8nC00 20 Oct, 2008 3.20.20.30 Assigned
3c8nD00 20 Oct, 2008 3.20.20.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P9WNE1 FGD_MYCTU Mycobacterium tuberculosis H37Rv F420-dependent glucose-6-phosphate dehydrogenase
P9WNE1 FGD_MYCTU Mycobacterium tuberculosis H37Rv F420-dependent glucose-6-phosphate dehydrogenase
P9WNE1 FGD_MYCTU Mycobacterium tuberculosis H37Rv F420-dependent glucose-6-phosphate dehydrogenase
P9WNE1 FGD_MYCTU Mycobacterium tuberculosis H37Rv F420-dependent glucose-6-phosphate dehydrogenase