PDB 2zm3

PDB Information

PDB2ZM3
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment
Mayer, S.C., Banker, A.L., Boschelli, F., Di, L., Johnson, M., Kenny, C.H., Krishnamurthy, G., Kutterer, K., Moy, F., Petusky, S., Ravi, M., Tkach, D., Tsou, H.R., Xu, W.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2008-04-10
Resolution2.500
CATH Insert Date23 Jul, 2008

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped
B 24 Jul, 2008 Chopped
C 24 Jul, 2008 Chopped
D 24 Jul, 2008 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2zm3A01 31 Mar, 2009 3.30.200.20 Assigned
2zm3A02 31 Mar, 2009 1.10.510.10 Assigned
2zm3B01 01 Apr, 2009 3.30.200.20 Assigned
2zm3B02 01 Apr, 2009 1.10.510.10 Assigned
2zm3C01 01 Apr, 2009 3.30.200.20 Assigned
2zm3C02 01 Apr, 2009 1.10.510.10 Assigned
2zm3D01 31 Mar, 2009 3.30.200.20 Assigned
2zm3D02 31 Mar, 2009 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor
P08069 IGF1R_HUMAN Homo sapiens Insulin-like growth factor 1 receptor