PDB 2ym8

PDB Information

PDB2YM8
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Structure-Guided Evolution of Potent and Selective Chk1 Inhibitors Through Scaffold Morphing.
Reader, J.C., Matthews, T.P., Klair, S., Cheung, K.M.J., Scanlon, J., Proisy, N., Addison, G., Ellard, J., Piton, N., Taylor, S., Cherry, M., Fisher, M., Boxall, K., Burns, S., Walton, M.I., Westwood, I.M., Hayes, A., Eve, P., Valenti, M., De Haven Brandon, A., Box, G., Van Montfort, R.L.M., Williams, D.H., Aherne, G.W., Raynaud, F.I., Eccles, S.A., Garrett, M.D., Collins, I.
J.Med.Chem.
HeaderTransferase
Released2011-06-06
Resolution2.070
CATH Insert Date15 Jan, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Jan, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ym8A01 19 Jan, 2012 3.30.200.20 Assigned
2ym8A02 19 Jan, 2012 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1