PDB 2ydw

PDB Information

PDB2YDW
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Discovery and Characterization of Small Molecule Inhibitors of the Bet Family Bromodomains.
Chung, C.W., Coste, H., White, J.H., Mirguet, O., Wilde, J., Gosmini, R.L., Delves, C., Magny, S.M., Woodward, R., Hughes, S.A., Boursier, E.V., Flynn, H., Bouillot, A.M., Bamborough, P., Brusq, J.M., Gellibert, F.J., Jones, E.J., Riou, A.M., Homes, P., Martin, S.L., Uings, I.J., Toum, J., Clement, C.A., Boullay, A.B., Grimley, R.L., Blandel, F.M., Prinjha, R.K., Lee, K., Kirilovsky, J., Nicodeme, E.
J.Med.Chem.
HeaderNuclear Protein
Released2011-03-24
Resolution1.900
CATH Insert Date19 Jun, 2011

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2011 Chopped
B 20 Jun, 2011 Chopped
C 20 Jun, 2011 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2ydwA00 22 Jun, 2011 1.20.920.10 Assigned
2ydwB00 23 Jun, 2011 1.20.920.10 Assigned
2ydwC00 23 Jun, 2011 1.20.920.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2
P25440 BRD2_HUMAN Homo sapiens Bromodomain-containing protein 2