PDB 2ydj

PDB Information

PDB2YDJ
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-Fluorophenyl)-N-(Piperidin-3-Yl)-3-Ureidothiophene-2-Carboxamide (Azd7762) by Structure-Based Design and Optimization of Thiophenecarboxamide Ureas.
Oza, V., Ashwell, S., Almeida, L., Brassil, P., Breed, J., Deng, C., Gero, T., Grondine, M., Horn, C., Ioannidis, S., Liu, D., Lyne, P., Newcombe, N., Pass, M., Read, J.A., Ready, S., Rowsell, S., Su, M., Toader, D., Vasbinder, M., Yu, D., Yu, Y., Xue, Y., Zabludoff, S., Janetka, J.
J.Med.Chem.
HeaderTransferase
Released2011-03-22
Resolution1.850
CATH Insert Date29 Jan, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 Jan, 2012 Chopped
B 30 Jan, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2ydjA01 01 Feb, 2012 3.30.200.20 Assigned
2ydjA02 01 Feb, 2012 1.10.510.10 Assigned
2ydjB01 02 Feb, 2012 3.30.200.20 Assigned
2ydjB02 02 Feb, 2012 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1