PDB 2xxi

PDB Links
Overview

PDB Information

PDB	2XXI
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	RATTUS NORVEGICUS
Primary Citation	Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of Ampa Receptor Positive Allosteric Modulators. Ward, S.E., Harries, M., Aldegheri, L., Austin, N.E., Ballantine, S., Ballini, E., Bradley, D.M., Bax, B.D., Clarke, B.P., Harris, A.J., Harrison, S.A., Melarange, R.A., Mookherjee, C., Mosley, J., Dal Negro, G., Oliosi, B., Smith, K.J., Thewlis, K.M., Woollard, P.M., Yusaf, S.P. J.Med.Chem.
Header	Transport Protein
Released	2010-11-10
Resolution	1.600
CATH Insert Date	10 Apr, 2011

PDB Images (10)

Image of CATH 2xxi

2xxi

PDB 2xxi

Image of CATH 2xxiA

2xxiA

PDB Chain 2xxiA

Image of CATH 2xxiB

2xxiB

PDB Chain 2xxiB

Image of CATH 2xxiC

2xxiC

PDB Chain 2xxiC

Image of CATH 2xxiA01

2xxiA01

CATH Domain 2xxiA01

Image of CATH 2xxiA02

2xxiA02

CATH Domain 2xxiA02

Image of CATH 2xxiB01

2xxiB01

CATH Domain 2xxiB01

Image of CATH 2xxiB02

2xxiB02

CATH Domain 2xxiB02

Image of CATH 2xxiC01

2xxiC01

CATH Domain 2xxiC01

Image of CATH 2xxiC02

2xxiC02

CATH Domain 2xxiC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2011	Chopped
B	11 Apr, 2011	Chopped
C	11 Apr, 2011	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2xxiA01	13 Apr, 2011	3.40.190.10	Assigned
2xxiA02	13 Apr, 2011	3.40.190.10	Assigned
2xxiB01	13 Apr, 2011	3.40.190.10	Assigned
2xxiB02	13 Apr, 2011	3.40.190.10	Assigned
2xxiC01	13 Apr, 2011	3.40.190.10	Assigned
2xxiC02	13 Apr, 2011	3.40.190.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2