PDB 2xxh

PDB Links
Overview

PDB Information

PDB	2XXH
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	RATTUS NORVEGICUS
Primary Citation	Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of Ampa Receptor Positive Allosteric Modulators. Ward, S.E., Harries, M., Aldegheri, L., Austin, N.E., Ballantine, S., Ballini, E., Bradley, D.M., Bax, B.D., Clarke, B.P., Harris, A.J., Harrison, S.A., Melarange, R.A., Mookherjee, C., Mosley, J., Dal Negro, G., Oliosi, B., Smith, K.J., Thewlis, K.M., Woollard, P.M., Yusaf, S.P. J.Med.Chem.
Header	Transport Protein
Released	2010-11-10
Resolution	1.500
CATH Insert Date	10 Apr, 2011

PDB Images (10)

Image of CATH 2xxh

2xxh

PDB 2xxh

Image of CATH 2xxhA

2xxhA

PDB Chain 2xxhA

Image of CATH 2xxhB

2xxhB

PDB Chain 2xxhB

Image of CATH 2xxhC

2xxhC

PDB Chain 2xxhC

Image of CATH 2xxhA01

2xxhA01

CATH Domain 2xxhA01

Image of CATH 2xxhA02

2xxhA02

CATH Domain 2xxhA02

Image of CATH 2xxhB01

2xxhB01

CATH Domain 2xxhB01

Image of CATH 2xxhB02

2xxhB02

CATH Domain 2xxhB02

Image of CATH 2xxhC01

2xxhC01

CATH Domain 2xxhC01

Image of CATH 2xxhC02

2xxhC02

CATH Domain 2xxhC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2011	Chopped
B	11 Apr, 2011	Chopped
C	11 Apr, 2011	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2xxhA01	13 Apr, 2011	3.40.190.10	Assigned
2xxhA02	13 Apr, 2011	3.40.190.10	Assigned
2xxhB01	13 Apr, 2011	3.40.190.10	Assigned
2xxhB02	13 Apr, 2011	3.40.190.10	Assigned
2xxhC01	13 Apr, 2011	3.40.190.10	Assigned
2xxhC02	13 Apr, 2011	3.40.190.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2