PDB 2xx8

PDB Links
Overview

PDB Information

PDB	2XX8
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	RATTUS NORVEGICUS
Primary Citation	Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of Ampa Receptor Positive Allosteric Modulators. Ward, S.E., Harries, M., Aldegheri, L., Austin, N.E., Ballantine, S., Ballini, E., Bradley, D.M., Bax, B.D., Clarke, B.P., Harris, A.J., Harrison, S.A., Melarange, R.A., Mookherjee, C., Mosley, J., Dal Negro, G., Oliosi, B., Smith, K.J., Thewlis, K.M., Woollard, P.M., Yusaf, S.P. J.Med.Chem.
Header	Transport Protein
Released	2010-11-09
Resolution	1.550
CATH Insert Date	08 May, 2011

PDB Images (10)

Image of CATH 2xx8

2xx8

PDB 2xx8

Image of CATH 2xx8A

2xx8A

PDB Chain 2xx8A

Image of CATH 2xx8B

2xx8B

PDB Chain 2xx8B

Image of CATH 2xx8C

2xx8C

PDB Chain 2xx8C

Image of CATH 2xx8A01

2xx8A01

CATH Domain 2xx8A01

Image of CATH 2xx8A02

2xx8A02

CATH Domain 2xx8A02

Image of CATH 2xx8B01

2xx8B01

CATH Domain 2xx8B01

Image of CATH 2xx8B02

2xx8B02

CATH Domain 2xx8B02

Image of CATH 2xx8C01

2xx8C01

CATH Domain 2xx8C01

Image of CATH 2xx8C02

2xx8C02

CATH Domain 2xx8C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	09 May, 2011	Chopped
B	09 May, 2011	Chopped
C	09 May, 2011	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2xx8A01	15 May, 2011	3.40.190.10	Assigned
2xx8A02	15 May, 2011	3.40.190.10	Assigned
2xx8B01	14 May, 2011	3.40.190.10	Assigned
2xx8B02	14 May, 2011	3.40.190.10	Assigned
2xx8C01	15 May, 2011	3.40.190.10	Assigned
2xx8C02	15 May, 2011	3.40.190.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2