PDB 2xx7

PDB Links
Overview

PDB Information

PDB	2XX7
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	RATTUS NORVEGICUS
Primary Citation	Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of Ampa Receptor Positive Allosteric Modulators. Ward, S.E., Harries, M., Aldegheri, L., Austin, N.E., Ballantine, S., Ballini, E., Bradley, D.M., Bax, B.D., Clarke, B.P., Harris, A.J., Harrison, S.A., Melarange, R.A., Mookherjee, C., Mosley, J., Dal Negro, G., Oliosi, B., Smith, K.J., Thewlis, K.M., Woollard, P.M., Yusaf, S.P. J.Med.Chem.
Header	Transport Protein
Released	2010-11-09
Resolution	2.200
CATH Insert Date	10 Apr, 2011

PDB Images (10)

Image of CATH 2xx7

2xx7

PDB 2xx7

Image of CATH 2xx7A

2xx7A

PDB Chain 2xx7A

Image of CATH 2xx7B

2xx7B

PDB Chain 2xx7B

Image of CATH 2xx7C

2xx7C

PDB Chain 2xx7C

Image of CATH 2xx7A01

2xx7A01

CATH Domain 2xx7A01

Image of CATH 2xx7A02

2xx7A02

CATH Domain 2xx7A02

Image of CATH 2xx7B01

2xx7B01

CATH Domain 2xx7B01

Image of CATH 2xx7B02

2xx7B02

CATH Domain 2xx7B02

Image of CATH 2xx7C01

2xx7C01

CATH Domain 2xx7C01

Image of CATH 2xx7C02

2xx7C02

CATH Domain 2xx7C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2011	Chopped
B	11 Apr, 2011	Chopped
C	11 Apr, 2011	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2xx7A01	13 Apr, 2011	3.40.190.10	Assigned
2xx7A02	13 Apr, 2011	3.40.190.10	Assigned
2xx7B01	13 Apr, 2011	3.40.190.10	Assigned
2xx7B02	13 Apr, 2011	3.40.190.10	Assigned
2xx7C01	12 Apr, 2011	3.40.190.10	Assigned
2xx7C02	12 Apr, 2011	3.40.190.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2