PDB Information

PDB2XQB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Engineering a High Affinity Anti-Il-15 Antibody: Crystal Structure Reveals an Alpha-Helix in Vh Cdr3 as Key Component of Paratope.
Lowe, D.C., Gerhardt, S., Ward, A., Hargreaves, D., Anderson, M., Ferraro, F., Pauptit, R.A., Pattison, D.V., Buchanan, C., Popovic, B., Finch, D.K., Wilkinson, T., Sleeman, M., Vaughan, T.J., Mallinder, P.R.
J.Mol.Biol.
HeaderImmune System
Released2010-09-01
Resolution2.600
CATH Insert Date23 Jan, 2011

PDB Images (9)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped
H 24 Jan, 2011 Chopped
L 24 Jan, 2011 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
2xqbA00 04 Feb, 2013 1.20.1250.70 Assigned
2xqbH01 17 Feb, 2011 2.60.40.10 Assigned
2xqbH02 17 Feb, 2011 2.60.40.10 Assigned
2xqbL01 17 Feb, 2011 2.60.40.10 Assigned
2xqbL02 17 Feb, 2011 2.60.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P40933 IL15_HUMAN Homo sapiens Interleukin-15