PDB 2xno

PDB Information

PDB2XNO
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Benzimidazole Inhibitors Induce a Dfg-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship.
Solanki, S., Innocenti, P., Mas-Droux, C., Boxall, K., Barillari, C., Van Montfort, R.L., Aherne, G.W., Bayliss, R., Hoelder, S.
J.Med.Chem.
HeaderTransferase
Released2010-08-05
Resolution1.980
CATH Insert Date03 Apr, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Apr, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2xnoA01 07 Apr, 2011 3.30.200.20 Assigned
2xnoA02 07 Apr, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P51955 NEK2_HUMAN Homo sapiens Serine/threonine-protein kinase Nek2