PDB Information

PDB2XM8
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Structure-Based Design of Potent and Selective 2-(Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2.
Caldwell, J.J., Welsh, E.J., Matijssen, C., Anderson, V.E., Antoni, L., Boxall, K., Urban, F., Hayes, A., Raynaud, F.I., Rigoreau, L.J., Raynham, T., Aherne, G.W., Pearl, L.H., Oliver, A.W., Garrett, M.D., Collins, I.
J.Med.Chem.
HeaderTransferase
Released2010-07-26
Resolution3.400
CATH Insert Date23 Jan, 2011

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Jan, 2011 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2xm8A01 12 Jul, 2011 3.30.200.20 Assigned
2xm8A02 12 Jul, 2011 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O96017 CHK2_HUMAN Homo sapiens Serine/threonine-protein kinase Chk2