PDB Information

PDB2XCT
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceSTAPHYLOCOCCUS AUREUS
Primary Citation
Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Bax, B.D., Chan, P.F., Eggleston, D.S., Fosberry, A., Gentry, D.R., Gorrec, F., Giordano, I., Hann, M.M., Hennessy, A., Hibbs, M., Huang, J., Jones, E., Jones, J., Brown, K.K., Lewis, C.J., May, E.W., Saunders, M.R., Singh, O., Spitzfaden, C., Shen, C., Shillings, A., Theobald, A.F., Wohlkonig, A., Pearson, N.D., Gwynn, M.N.
Nature
HeaderIsomerase/Dna/Antibiotic
Released2010-04-25
Resolution3.350
CATH Insert Date29 Aug, 2010

PDB Images (21)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
B 30 Aug, 2010 Chopped
D 30 Aug, 2010 Chopped
E 30 Aug, 2010 Rejected
F 30 Aug, 2010 Rejected
G 30 Aug, 2010 Rejected
H 30 Aug, 2010 Rejected
S 30 Aug, 2010 Chopped
U 30 Aug, 2010 Chopped
V 30 Aug, 2010 Rejected
W 30 Aug, 2010 Rejected
X 30 Aug, 2010 Rejected
Y 30 Aug, 2010 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2xctB01 13 Nov, 2013 3.40.50.670 Assigned
2xctB02 13 Nov, 2013 Holding pen
2xctD01 13 Nov, 2013 3.40.50.670 Assigned
2xctD02 13 Nov, 2013 Holding pen
2xctS01 13 Nov, 2013 3.40.50.670 Assigned
2xctS02 13 Nov, 2013 Holding pen
2xctU01 11 Sep, 2013 3.40.50.670 Assigned
2xctU02 11 Sep, 2013 Holding pen

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A