PDB Information

PDB2XCR
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceSTAPHYLOCOCCUS AUREUS
Primary Citation
Type Iia Topoisomerase Inhibition by a New Class of Antibacterial Agents.
Bax, B.D., Chan, P.F., Eggleston, D.S., Fosberry, A., Gentry, D.R., Gorrec, F., Giordano, I., Hann, M.M., Hennessy, A., Hibbs, M., Huang, J., Jones, E., Jones, J., Brown, K.K., Lewis, C.J., May, E.W., Saunders, M.R., Singh, O., Spitzfaden, C., Shen, C., Shillings, A., Theobald, A.F., Wohlkonig, A., Pearson, N.D., Gwynn, M.N.
Nature
HeaderIsomerase
Released2010-04-25
Resolution3.500
CATH Insert Date15 Aug, 2010

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
B 16 Aug, 2010 Chopped
D 16 Aug, 2010 Chopped
E 16 Aug, 2010 Rejected
F 16 Aug, 2010 Rejected
S 16 Aug, 2010 Chopped
U 16 Aug, 2010 Chopped
V 16 Aug, 2010 Rejected
W 16 Aug, 2010 Rejected

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
2xcrB01 24 Sep, 2013 3.40.50.670 Assigned
2xcrB02 24 Sep, 2013 3.90.199.10 Assigned
2xcrB03 24 Sep, 2013 3.30.1360.40 Assigned
2xcrB04 24 Sep, 2013 1.10.268.10 Assigned
2xcrD01 24 Sep, 2013 3.40.50.670 Assigned
2xcrD02 24 Sep, 2013 3.90.199.10 Assigned
2xcrD03 24 Sep, 2013 3.30.1360.40 Assigned
2xcrD04 24 Sep, 2013 1.10.268.10 Assigned
2xcrS01 24 Sep, 2013 3.40.50.670 Assigned
2xcrS02 24 Sep, 2013 3.90.199.10 Assigned
2xcrS03 24 Sep, 2013 3.30.1360.40 Assigned
2xcrS04 24 Sep, 2013 1.10.268.10 Assigned
2xcrU01 24 Sep, 2013 3.40.50.670 Assigned
2xcrU02 24 Sep, 2013 3.90.199.10 Assigned
2xcrU03 24 Sep, 2013 3.30.1360.40 Assigned
2xcrU04 24 Sep, 2013 1.10.268.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
Q99XG5 GYRA_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit A
P66937 GYRB_STAAN Staphylococcus aureus subsp. aureus N315 DNA gyrase subunit B