PDB 2x8i

PDB Information

PDB2X8I
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of a Novel Class of Triazolones as Checkpoint Kinase Inhibitors-Hit to Lead Exploration.
Oza, V., Ashwell, S., Brassil, P., Breed, J., Deng, C., Ezhuthachan, J., Haye, H., Horn, C., Janetka, J., Lyne, P., Newcombe, N., Otterbien, L., Pass, M., Read, J.A., Roswell, S., Su, M., Toader, D., Yu, D., Yu, Y., Valentine, A., Webborn, P., White, A., Zabludoff, S., Zheng, X.
Bioorg.Med.Chem.
HeaderTransferase
Released2010-03-09
Resolution1.920
CATH Insert Date15 Aug, 2010

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2010 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2x8iA01 24 Aug, 2010 3.30.200.20 Assigned
2x8iA02 24 Aug, 2010 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1