PDB 2x7o

PDB Information

PDB2X7O
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Design, Synthesis and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor Beta Receptor I (Tgfbri)
Roth, G.J., Heckel, A., Brandl, T., Grauert, M., Hoerer, S., Kley, J.T., Schnapp, G., Baum, P., Mennerich, D., Schnapp, A., Park, J.E.
J.Med.Chem.
HeaderTransferase
Released2010-03-03
Resolution3.700
CATH Insert Date24 Oct, 2010

PDB Images (16)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 25 Oct, 2010 Chopped
B 25 Oct, 2010 Chopped
C 25 Oct, 2010 Chopped
D 25 Oct, 2010 Chopped
E 25 Oct, 2010 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
2x7oA01 05 Nov, 2010 3.30.200.20 Assigned
2x7oA02 05 Nov, 2010 1.10.510.10 Assigned
2x7oB01 06 Nov, 2010 3.30.200.20 Assigned
2x7oB02 06 Nov, 2010 1.10.510.10 Assigned
2x7oC01 06 Nov, 2010 3.30.200.20 Assigned
2x7oC02 06 Nov, 2010 1.10.510.10 Assigned
2x7oD01 05 Nov, 2010 3.30.200.20 Assigned
2x7oD02 05 Nov, 2010 1.10.510.10 Assigned
2x7oE01 06 Nov, 2010 3.30.200.20 Assigned
2x7oE02 06 Nov, 2010 1.10.510.10 Assigned

UniProtKB Entries (5)

Accession Gene ID Taxon Description
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1
P36897 TGFR1_HUMAN Homo sapiens TGF-beta receptor type-1