PDB Information

PDB2WKS
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHELICOBACTER PYLORI
Primary Citation
Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.
Prazeres, V.F., Tizon, L., Otero, J.M., Guardado-Calvo, P., Llamas-Saiz, A.L., van Raaij, M.J., Castedo, L., Lamb, H., Hawkins, A.R., Gonzalez-Bello, C.
J. Med. Chem.
HeaderLyase
Released2009-06-17
Resolution2.950
CATH Insert Date03 Dec, 2009

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 03 Dec, 2009 Chopped
B 03 Dec, 2009 Chopped
C 03 Dec, 2009 Chopped
D 03 Dec, 2009 Chopped
E 03 Dec, 2009 Chopped
F 03 Dec, 2009 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
2wksA00 06 Dec, 2009 3.40.50.9100 Assigned
2wksB00 06 Dec, 2009 3.40.50.9100 Assigned
2wksC00 06 Dec, 2009 3.40.50.9100 Assigned
2wksD00 05 Dec, 2009 3.40.50.9100 Assigned
2wksE00 06 Dec, 2009 3.40.50.9100 Assigned
2wksF00 06 Dec, 2009 3.40.50.9100 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q48255 AROQ_HELPY Helicobacter pylori 26695 3-dehydroquinate dehydratase
Q48255 AROQ_HELPY Helicobacter pylori 26695 3-dehydroquinate dehydratase
Q48255 AROQ_HELPY Helicobacter pylori 26695 3-dehydroquinate dehydratase
Q48255 AROQ_HELPY Helicobacter pylori 26695 3-dehydroquinate dehydratase
Q48255 AROQ_HELPY Helicobacter pylori 26695 3-dehydroquinate dehydratase
Q48255 AROQ_HELPY Helicobacter pylori 26695 3-dehydroquinate dehydratase