PDB Information

PDB2WK3
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Molecular Basis for the Recognition and Cleavages of Igf-II, Tgf-Alpha, and Amylin by Human Insulin Degrading Enzyme.
Guo, Q., Manolopoulou, M., Bian, Y., Schilling, A.B., Tang, W.J.
J.Mol.Biol.
HeaderHydrolase
Released2009-06-05
Resolution2.590
CATH Insert Date15 Nov, 2009

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2009 Chopped
B 15 Nov, 2009 Chopped
C 15 Nov, 2009 Rejected
D 15 Nov, 2009 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2wk3A01 30 Aug, 2013 3.30.830.10 Assigned
2wk3A02 30 Aug, 2013 3.30.830.10 Assigned
2wk3A03 30 Aug, 2013 3.30.830.10 Assigned
2wk3A04 30 Aug, 2013 3.30.830.10 Assigned
2wk3B01 30 Aug, 2013 3.30.830.10 Assigned
2wk3B02 30 Aug, 2013 3.30.830.10 Assigned
2wk3B03 30 Aug, 2013 3.30.830.10 Assigned
2wk3B04 30 Aug, 2013 3.30.830.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P05067 A4_HUMAN Homo sapiens Amyloid-beta precursor protein
P05067 A4_HUMAN Homo sapiens Amyloid-beta precursor protein