PDB 2w2q

PDB Links
Overview

PDB Information

PDB	2W2Q
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants. Bottomley, M.J., Cirillo, A., Orsatti, L., Ruggeri, L., Fisher, T.S., Santoro, J.C., Cummings, R.T., Cubbon, R.M., Lo Surdo, P., Calzetta, A., Noto, A., Baysarowich, J., Mattu, M., Talamo, F., De Francesco, R., Sparrow, C.P., Sitlani, A., Carfi, A. J.Biol.Chem.
Header	Hydrolase/Receptor
Released	2008-11-03
Resolution	2.330
CATH Insert Date	20 Nov, 2008

PDB Images (7)

Image of CATH 2w2q

2w2q

PDB 2w2q

Image of CATH 2w2qA

2w2qA

PDB Chain 2w2qA

Image of CATH 2w2qE

2w2qE

PDB Chain 2w2qE

Image of CATH 2w2qP

2w2qP

PDB Chain 2w2qP

Image of CATH 2w2qA00

2w2qA00

CATH Domain 2w2qA00

Image of CATH 2w2qE00

2w2qE00

CATH Domain 2w2qE00

Image of CATH 2w2qP01

2w2qP01

CATH Domain 2w2qP01

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	20 Nov, 2008	Chopped
E	20 Nov, 2008	Chopped
P	20 Nov, 2008	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2w2qA00	21 Nov, 2008	3.40.50.200	Assigned
2w2qE00	01 Jul, 2013	2.10.25.10	Assigned
2w2qP01	04 Feb, 2013	3.30.70.80	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P01130	LDLR_HUMAN	Homo sapiens	Low-density lipoprotein receptor
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9