PDB 2w2m

PDB Links
Overview

PDB Information

PDB	2W2M
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Structural and Biochemical Characterization of the Wild Type Pcsk9/Egf-Ab Complex and Natural Fh Mutants. Bottomley, M.J., Cirillo, A., Orsatti, L., Ruggeri, L., Fisher, T.S., Santoro, J.C., Cummings, R.T., Cubbon, R.M., Lo Surdo, P., Calzetta, A., Noto, A., Baysarowich, J., Mattu, M., Talamo, F., De Francesco, R., Sparrow, C.P., Sitlani, A., Carfi, A. J.Biol.Chem.
Header	Hydrolase/Receptor
Released	2008-11-03
Resolution	2.400
CATH Insert Date	20 Nov, 2008

PDB Images (7)

Image of CATH 2w2m

2w2m

PDB 2w2m

Image of CATH 2w2mA

2w2mA

PDB Chain 2w2mA

Image of CATH 2w2mE

2w2mE

PDB Chain 2w2mE

Image of CATH 2w2mP

2w2mP

PDB Chain 2w2mP

Image of CATH 2w2mA00

2w2mA00

CATH Domain 2w2mA00

Image of CATH 2w2mE00

2w2mE00

CATH Domain 2w2mE00

Image of CATH 2w2mP01

2w2mP01

CATH Domain 2w2mP01

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	20 Nov, 2008	Chopped
E	20 Nov, 2008	Chopped
P	20 Nov, 2008	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2w2mA00	21 Nov, 2008	3.40.50.200	Assigned
2w2mE00	01 Jul, 2013	2.10.25.10	Assigned
2w2mP01	04 Feb, 2013	3.30.70.80	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9
P01130	LDLR_HUMAN	Homo sapiens	Low-density lipoprotein receptor
Q8NBP7	PCSK9_HUMAN	Homo sapiens	Proprotein convertase subtilisin/kexin type 9