PDB 2vnn

PDB Information

PDB2VNN
MethodX-RAY DIFFRACTION
Host OrganismCRICETULUS GRISEUS
Gene SourceHOMO SAPIENS
Primary Citation
Second Generation of Hydroxyethylamine Bace-1 Inhibitors: Optimizing Potency and Oral Bioavailability.
Charrier, N., Clarke, B., Cutler, L., Demont, E., Dingwall, C., Dunsdon, R., East, P., Hawkins, J., Howes, C., Hussain, I., Jeffrey, P., Maile, G., Matico, R., Mosley, J., Naylor, A., O'Brien, A., Redshaw, S., Rowland, P., Soleil, V., Smith, K.J., Sweitzer, S., Theobald, P., Vesey, D., Walter, D.S., Wayne, G.
J.Med.Chem.
HeaderHydrolase
Released2008-02-05
Resolution1.870
CATH Insert Date23 Jul, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Jul, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2vnnA01 25 Jul, 2008 2.40.70.10 Assigned
2vnnA02 25 Jul, 2008 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1