PDB Information

PDB2R9N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and Synthesis of Reversible Inhibitors of Cathepsin S: alpha,alpha-Disubstitution at the P1 Residue Provides Potent Inhibitors in Cellular Assays and In Vivo Models of Antigen Presentation
Ward, Y.D., Emmanuel, M.J., Thomson, D.S., Liu, W., Bekkali, Y., Frye, L.L., Girardot, M., Morwick, T., Young, E.R.R., Zindell, R., Hrapchak, M., DeTuri, M., White, A., Crane, K.M., White, D.M., Wang, Y., Hao, M.-H., Grygon, C.A., Labadia, M.E., Wildeson, J., Freeman, D., Nelson, R., Capolino, A., Peterson, J.D., Raymond, E.L., Brown, M.L., Spero, D.M.
to be published
HeaderHydrolase
Released2007-09-13
Resolution2.000
CATH Insert Date20 Dec, 2007

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 20 Dec, 2007 Chopped
B 20 Dec, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2r9nA00 21 Dec, 2007 3.90.70.10 Assigned
2r9nB00 21 Dec, 2007 3.90.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P25774 CATS_HUMAN Homo sapiens Cathepsin S
P25774 CATS_HUMAN Homo sapiens Cathepsin S