PDB 2r0u

PDB Information

PDB2R0U
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase.
Garbaccio, R.M., Huang, S., Tasber, E.S., Fraley, M.E., Yan, Y., Munshi, S., Ikuta, M., Kuo, L., Kreatsoulas, C., Stirdivant, S., Drakas, B., Rickert, K., Walsh, E.S., Hamilton, K.A., Buser, C.A., Hardwick, J., Mao, X., Beck, S.C., Abrams, M.T., Tao, W., Lobell, R., Sepp-Lorenzino, L., Hartman, G.D.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2007-08-21
Resolution1.900
CATH Insert Date07 Nov, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2r0uA01 23 Nov, 2007 3.30.200.20 Assigned
2r0uA02 23 Nov, 2007 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1