PDB Information

PDB2QZL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
BACE-1 inhibition by a series of psi[CH2NH] reduced amide isosteres
Coburn, C.A., Stachel, S.J., Jones, K.G., Steele, T.G., Rush, D.M., DiMuzio, J., Pietrak, B.L., Lai, M.T., Huang, Q., Lineberger, J., Jin, L., Munshi, S., Holloway, K.M., Espeseth, A., Simon, A., Hazuda, D., Graham, S.L., Vacca, J.P.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-08-16
Resolution1.800
CATH Insert Date24 Apr, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Apr, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2qzlA01 25 Apr, 2008 2.40.70.10 Assigned
2qzlA02 25 Apr, 2008 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1