PDB Information

PDB2QP8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Potent pyrrolidine- and piperidine-based BACE-1 inhibitors.
Iserloh, U., Wu, Y., Cumming, J.N., Pan, J., Wang, L.Y., Stamford, A.W., Kennedy, M.E., Kuvelkar, R., Chen, X., Parker, E.M., Strickland, C., Voigt, J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-07-23
Resolution1.500
CATH Insert Date13 Mar, 2008

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 13 Mar, 2008 Chopped
B 13 Mar, 2008 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2qp8A01 14 Mar, 2008 2.40.70.10 Assigned
2qp8A02 14 Mar, 2008 2.40.70.10 Assigned
2qp8B01 14 Mar, 2008 2.40.70.10 Assigned
2qp8B02 14 Mar, 2008 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1